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A widely used fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorometrically. λex: 340 - 360 nm; λem: 440 - 460 nm.
For cells, cell lines and tissues in culture till half confluency.
Suc-LLVY-AMC; Proteasome Substrate; Calpain Substrate
Protect from moisture and light
C₄₀H₅₃N₅O₁₀
Suc-Leu-Leu-Val-Tyr-AMC
Lyophilized solid
≥98% by HPLC
DMSO (~ 5 mM)
Biochemicals
94367-21-2
24 months
gel pack
763.88
-20°C
cell
N/A
No
No