MC5 Receptor/MC5-R Antibody, FITC Conjugated

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Size

0.1ml

Catalog no

bs-11418R-FITC
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Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Antigen background

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic peptide derived from human MC5 Receptor

Specificity

This is a highly specific antibody against MC5 Receptor/MC5-R.

Long name

MC5 Receptor/MC5-R Polyclonal Antibody, FITC Conjugated

Synonyms

MC2; Melanocortin receptor 5; MC5-R; MC-2; MC5R

Purification method

This antibody was purified via Protein A.

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200)

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Clone

Polyclonal antibody

Additional conjugation

Anti-FITC Antibody

Target Antigen

MC5 Receptor/MC5-R

Tested applications

FCM, IF(IHC-P)

Subcellular location

Extracellular

Crossreactivity

Human, Mouse

Concentration

1ug per 1ul

Excitation Emission

494nm/518nm

Immunogen_range

98-114/325

Clonality

Polyclonal

Modification

Unmodified

French translation

anticorps

Swiss Prot

P33032

Modification site

None

Conjugation

FITC

Gene ID number

4161

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