SMC1 Antibody, Cy5.5 Conjugated

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Size

0.1ml

Catalog no

bs-3568R-Cy5.5
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Antigen background

Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Synonyms

SMC1; SMCB; CDLS2; SB1.8; SMC1L1; DXS423E; SMC1alpha; Structural maintenance of chromosomes protein 1A; SMC protein 1A; SMC-1-alpha; SMC-1A; SMC1A; KIAA0178

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Conjugated

These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.

Source

KLH conjugated synthetic peptide derived from human SMC1

Specificity

This is a highly specific antibody against SMC1.

Long name

SMC1 Polyclonal Antibody, Cy5.5 Conjugated

Purification method

This antibody was purified via Protein A.

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human, Mouse, Rat

Immunogen_range

150-200/1233

Excitation Emission

675nm/694nm

Additional conjugation

Cy5.5,Cy5.5

Concentration

1ug per 1ul

Clonality

Polyclonal

Modification

Unmodified

French translation

anticorps

Tested applications

IF(IHC-P)

Subcellular location

Nucleus

Swiss Prot

Q14683

Conjugation

Cy5.5

Modification site

None

Target Antigen

SMC1

Gene ID number

8243

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