GEMC1 Antibody, Cy5.5 Conjugated

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Size

0.1ml

Catalog no

bs-13332R-Cy5.5
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Antigen background

GEMC1 is a 334 amino acid nuclear protein that regulates DNA replication by promoting the recruitment of Cdc45 onto replication origins. A member of the GEMC1 family, GEMC1 is highly phosphorylated and interacts with chromatin during formation of the pre-replication complex. The gene encoding GEMC1 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Conjugated

These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.

Synonyms

GEMC1; Geminin coiled coil domain containing protein 1; Gm606; GEMC1_HUMAN.

Source

KLH conjugated synthetic peptide derived from human GEMC1

Specificity

This is a highly specific antibody against GEMC1.

Long name

GEMC1 Polyclonal Antibody, Cy5.5 Conjugated

Purification method

This antibody was purified via Protein A.

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human, Mouse, Rat

Excitation Emission

675nm/694nm

Additional conjugation

Cy5.5,Cy5.5

Concentration

1ug per 1ul

Clonality

Polyclonal

Modification

Unmodified

Tested applications

IF(IHC-P)

French translation

anticorps

Gene ID number

647309

Target Antigen

GEMC1

Conjugation

Cy5.5

Modification site

None

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