Heparin Binding EGF-like Growth Factor (HB-EGF, HBEGF, Diphtheria Toxin Receptor, DT-R, DTR)

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Size

500ug

Catalog no

GEN603983
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Description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Storage and shipping

Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 

Specificity and cross-reactivity

Recognizes human Heparin Binding EGF-like Growth Factor (HB-EGF). Does not crossreact with recombinant human Amphiregulin, BTC, HRG-alpha, HRG-beta, EGF, TGF-alpha or recombinant mouse Epigen or Epiregulin.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Other names

heparin-binding EGF-like growth factor; Proheparin-binding EGF-like growth factor; proheparin-binding EGF-like growth factor; OTTHUMP00000159876; heparin-binding epidermal growth factor; diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); heparin-binding EGF-like growth factor; Diphtheria toxin receptor

Species reactivity

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Form/Appearance

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.

Purification method

Affinity Purified by Protein G affinity chromatography.

Gene name

HBEGF; HBEGF; DTR; DTS; DTSF; HEGFL; DTR; DTS; HEGFL

Gene name synonims

HBEGF; HBEGF; DTR; DTS; DTSF; HEGFL; DTR; DTS; HEGFL

Other gene names

HBEGF; HBEGF; DTR; DTS; DTSF; HEGFL; DTR; DTS; HEGFL

Tested applications:

ELISA (EL/EIA), Western Blot (WB), Neutralization

Also known as

Heparin Binding EGF-like Growth Factor

Concentration

~0.5 mg/ml (after reconstitution)

Source organism

Human (Homo sapiens)

Subcategory

Mnoclonal antibodies

Host organism

Mouse (Mus musculus)

Clonality

Monoclonal

Category

Antibodies

Clone

7H229

Immunoglobulin isotype

IgG2a

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