SMC1 Antibody, ALEXA FLUOR 350

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Size

100ul

Catalog no

bs-3568R-A350
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Background of the antigen

Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

SMC1; SMCB; CDLS2; SB1.8; SMC1L1; DXS423E; SMC1alpha; Structural maintenance of chromosomes protein 1A; SMC protein 1A; SMC-1-alpha; SMC-1A; SMC1A; KIAA0178

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SMC1

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Long name

SMC1 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

Specificity

This is a highly specific antibody against SMC1.

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Also known as

Anti-SMC1 PAb ALEXA FLUOR 350

Conjugation

Alexa Fluor,ALEXA FLUOR 350

Purification

Purified by Protein A.

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Conjugated with

ALEXA FLUOR® 350

Crossreactivity

Human, Mouse, Rat

Immunogen range

150-200/1233

Concentration

1ug per 1ul

Excitation emission

343nm/442nm

Modification

Unmodified

Clonality

Polyclonal

Tested applications

IF(IHC-P)

French translation

anticorps

Subcellular location

Nucleus

Swiss Prot

Q14683

Target Antigen

SMC1

Modification Site

None

Gene ID Number

8243

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