C1orf129 Antibody, ALEXA FLUOR 488

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Size

100ul

Catalog no

bs-15016R-A488
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Background of the antigen

Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf129 gene product has been provisionally designated C1orf129 pending further characterization.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-C1orf129 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Synonyms

Armadillo repeat containing 11; ARMC11; C1orf129; CA129_HUMAN; Chromosome 1 open reading frame 129; FLJ23550; RP5-1092L12.1; Uncharacterized protein C1orf129.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C1orf129

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Long name

C1orf129 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against C1orf129.

Also known as

Anti-C1orf129 PAb ALEXA FLUOR 488

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Purification

Purified by Protein A.

Clone

Polyclonal antibody

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human, Mouse, Rat

Conjugated with

ALEXA FLUOR® 488

Conjugation

Alexa Fluor

Concentration

1ug per 1ul

Excitation emission

499nm/519nm

Modification

Unmodified

Clonality

Polyclonal

Tested applications

IF(IHC-P)

French translation

anticorps

Target Antigen

C1orf129

Modification Site

None

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