Name: Anti-SKP1 (Polyclonal), ALEXA Fluor 594
SKU: 01010335809
Price: 489 EUR
Availability: InStock

Synonyms

Cyclin A/CDK2 associated p19; Cyclin A/CDK2 associated protein p19; Cyclin-A/CDK2-associated protein p19; EMC 19; EMC19; OCP 2; OCP II; OCP II protein; OCP-2; OCP-II; OCP2; OCPII; organ of Corti protein 2; Organ of Corti protein II; p19A; p19skp1; RNA polymerase II elongation factor like protein; RNA polymerase II elongation factor like protein OCP2; RNA polymerase II elongation factor-like protein; S phase kinase associated protein 1; S phase kinase associated protein 1A; S phase kinase associated protein 1A p19A; S-phase kinase-associated protein 1; SIII; Skp 1; SKP 1A; skp1; SKP1_HUMAN; SKP1A; TCEB1L; Transcription elongation factor B SIII polypeptide 1 like; Transcription Elongation Factor B 1 like; Transcription Elongation Factor B 1-like; Transcription elongation factor B; Transcription elongation factor B SIII polypeptide 1 like.

Background information

Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Cross reactive species

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Antigen Source

KLH conjugated synthetic peptide derived from human SKP1

Modification

No modification has been applied to this antibody

Specificity

This antibody reacts specifically with SKP1

Properties

For facs or microscopy Alexa 1 conjugate.

Host organism

Rabbit (Oryctolagus cuniculus)

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Type

Conjugated Primary Antibody

Group

Polyclonals and antibodies

Also known as

SKP1 Polyclonal Antibody

Purification method

Purified by Protein A.

Clone

Polyclonal Antibodies

Other name

Anti-SKP1 Polyclonal

Clonality

Polyclonal Antibody

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Conjugated with

ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

Concentration

1ug per 1ul

Excitation emission

590nm/617nm

Applications

IF(IHC-P)

Modification site

None

Target Protein/Peptide

SKP1

Gene ID

6500

Swiss Prot

N/A

Subcellular locations

N/A

Anti-SKP1 (Polyclonal), ALEXA Fluor 594

Size

Price

Catalog no

Click and buy. Our professional team will take care of your order immediately.