GDF15/MIC-1 Antibody, Biotin Conjugated

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Size

0.1ml

Catalog no

bs-3818R-Biotin
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Antigen background

Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

Synonyms

PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor; GDF15

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

KLH conjugated synthetic peptide derived from human GDF-15

Specificity

This is a highly specific antibody against GDF15/MIC-1.

Long name

GDF15/MIC-1 Polyclonal Antibody, Biotin Conjugated

Purification method

This antibody was purified via Protein A.

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500)

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Clone

Polyclonal antibody

Crossreactivity

Human, Mouse, Rat

Additional conjugation

Biotinylated

Immunogen_range

260-308/308

Target Antigen

GDF15/MIC-1

Concentration

1ug per 1ul

Clonality

Polyclonal

Modification

Unmodified

French translation

anticorps

Tested applications

WB, IHC-P

Subcellular location

Secreted

Swiss Prot

Q99988

Conjugation

Biotin

Modification site

None

Gene ID number

9518

Excitation Emission

N/A

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