Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFF-R, is a protein in humans is encoded by the TNFRSF13C gene. The gene is mapped to chromosome 22q13.1-q13.31. It has got 184 amino acid transmembrane protein which is 56% identical to the mouse protein. B cell-activating factor enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.