MC5 Receptor/MC5-R Antibody, ALEXA FLUOR 488

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Size

100ul

Catalog no

bs-11418R-A488
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Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-MC5 Receptor/MC5-R has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the antigen

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MC5 Receptor

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Long name

MC5 Receptor/MC5-R Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Specificity

This is a highly specific antibody against MC5 Receptor/MC5-R.

Synonyms

MC2; Melanocortin receptor 5; MC5-R; MC-2; MC5R

Also known as

Anti-MC5 Receptor/MC5-R PAb ALEXA FLUOR 488

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200)

Host Organism

Rabbit (Oryctolagus cuniculus)

Category

Conjugated Primary Antibodies

Purification

Purified by Protein A.

Clone

Polyclonal antibody

Target Antigen

MC5 Receptor/MC5-R

Conjugated with

ALEXA FLUOR® 488

Tested applications

FCM, IF(IHC-P)

Subcellular location

Extracellular

Crossreactivity

Human, Mouse

Conjugation

Alexa Fluor

Concentration

1ug per 1ul

Excitation emission

499nm/519nm

Modification

Unmodified

Immunogen range

98-114/325

Clonality

Polyclonal

French translation

anticorps

Swiss Prot

P33032

Modification Site

None

Gene ID Number

4161

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