Background of the target antigen
Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf81 gene product has been provisionally designated C6orf81 pending further characterization.