MSH gamma Antibody

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Background of the target antigen

This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].


This is a highly specific antibody against MSH gamma. This antibody will detect Pro-opiomelanocortin, as well as MSH gamma, due to the fact that this protein is contained within this chain, and is then cleaved to produce MSH gamma. MSH gamma itself is too small to be detected by WB.


If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.


This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MSH gamma

Synonym names

Gamma MSH; Melanocyte Stimulating Hormone; Melanotropin gamma; POMC; Proopiomelanocortin; COLI_HUMAN.

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Purification method

This antibody was purified via Protein A.

Recommended dilutions

IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Long name

MSH gamma Primary Polyclonal Antibody


Polyclonal antibody

Modification site(s)

Unmodified antibody

Clone number

Polyclonal antibody


Primary Antibodies

Cross reactivity

Human, Mouse, Rat

Tested Applications


Also known as

MSH gamma PAb




1ug per 1ul

French translation


Immunogen range


Target Antigen

MSH gamma

Subcellular location


Gene ID number




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