GDF15/MIC-1 Antibody

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Size

0.1ml

Catalog no

bs-3818R
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Background of the target antigen

Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.

Synonym names

PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; Growth/differentiation factor 15; Macrophage inhibitory cytokine 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factor; GDF15

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDF-15

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Specificity

This is a highly specific antibody against GDF15/MIC-1.

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Purification method

This antibody was purified via Protein A.

Long name

GDF15/MIC-1 Primary Polyclonal Antibody

Tested Applications

WB, IHC-P, IF(IHC-P)

Clone number

Polyclonal antibody

Clonality

Polyclonal antibody

Modification site(s)

Unmodified antibody

Category

Primary Antibodies

Cross reactivity

Human, Mouse, Rat

Also known as

GDF15/MIC-1 PAb

Conjugation

Unconjugated

Concentration

1ug per 1ul

Immunogen range

260-308/308

Target Antigen

GDF15/MIC-1

French translation

anticorps

Subcellular location

Secreted

Swiss Prot

Q99988

Gene ID number

9518

Modification(s)

None

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