Description
N terminal acetylation or CH3CO as epigenetic regulation of Nitric Oxide Synthase (NOS) Inhibitor HP-228 [Nle4- Gln5, D-Phe7, D-Trp9]-a-MSH (4-10) amide[Nitric Oxide Synthase] by NATs.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.